 Description:
Cefotaxime is a broad spectrum Cephalosporin for parenteral
Administration. It is bactericidal, and effective against
Gram negative and gram positive
Bacteria. Like staphylococci, Klebsiella, Haemophilus,
influenzae, Enterobactor,
Neisseria, Salmonella, Shigella, Serratia, Citrobacter.
Composition: Each vial contains: Cefotaxime
250mg/500mg/1.0gm
as Cefotaxime sodium.
Indications: Use in the respiratory tract
infections, urinary tract infections, bone & soft
tissue
Infections, Gonorrhoea, meningitis.
Contra Indications: Hypersensitivity to cephalosporins,
severe renal failure.
Special Precautions: If Pseudomembranous colitis
occurs drugs should be discontinued.
Paediatrics: Safe.
Pregnancy & Lactation: Use only if clearly
indicated.
Side effects: Urticaria, drug fever, anaphylaxis,
Nausea, Vomiting, diarrhoea, eosinophillia, Thrombocytopenia,
leucopoenia.
Drug Interactions: Concurrent use of aminoglycosides
and frusemide leads to nephrotoxicity.
Dosage: Adults: 2 to 6 gm. daily in divided dose
Children: 100 to 150-mg/kg-body weight daily in divided
doses.
Presentation: Vials of 250mg/500mg/1.0 gm
Cefotaxime with sterile
Water for injection.
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