Indications: Streptomycin is indicated in all form of Mycobacterium tuberculosis infections, in conjunction with other antituberculous agent when the infecting organisms are susceptible to these drugs. The common combined drug therapy is streptomycin, isoniazid, and Para-amino-salicylic acid. Streptomycin is considered therapeutically as a first-line or primary antitubercular agent.
Non tuberculosis Infection: Streptomycin is indicated in those serious non tuberculosis infection caused by the bacterial organism shown to be sensitive to it and less potentially hazardous therapeutic agents are ineffective are contra-indicated. These are (a) Pasteurella Pestis (plague), (b) Pasteurella tularensis (tularemia), (c) Brucella, (d) dovonanosis (granuloma inguinale), (e) H. dureyi (chancroid), (f) H. influenzae (in respiratory, endocrinal and meningeal infections-concomitantly with other antibiotics), (g) K.pneumoniae and strept. Faecalis in urinary tract infections.

Contra Indications: A main disadvantage of streptomycin therapy is the development of bacterial resistance when used for a long period so used in combination therapy. Disease of ear partic, otitis media, labirynthine disturbances.

Special Precautions: Impaired liver or Kidneys function, premature infants, possibility of resistance, skin, Sensitization.

Paediatrics: Contra indicated.

Lactation& Pregnancy: Contra indicated.

Dosage: 1 gm in a day for 2-3 months or as prescribed by the Physician.

Presentation: Box of 25 vials of Streptomycin. 0.75g Box of 25 vials of Streptomycin. 1.0g