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Composition:
Each tablet Contains:
Penicillin G Potassium 400mg
Description:
It is a beta lactum antibiotic and is an derivative
of Penicillin called Benzyl Penicillin.It is an
narrow spectrum antibiotic and has a limited activity
against Gram Positive Bacteria. It acts by interfering
with cell wall mucopeptide synthesis so that organisms
explode from internal pressure. Penicillin is
thus bactericidal and is active against multiplying
organisms since resting animals are not making
new cells. It is active against gram Positive
Bacilli, Both Gram Negative and Gram Positive
cocci and spirochaetes. Absorption through GIT
is rapid in infants and elderly and is mainly
distributed extracellularly. Penetration through
CSF and serous cavities is poor .
To prevent it from gastric acid and for its maximum
absorption through GIT coating of Penicillin G
Potassium granules is done.
Indications:
* In streptococcal infections like Pharyngitis,
Otitis media, scarlet fever, Rheumatic fever.
· For Pneumococcal infections like otitis
media.
· For meningiococcal infections like meningitis,
Osteomyelitis.
· Used for treatment of gonorrhoea, syphilis,
diptheria, tetnus, gas gangrene , Trench mouth,
rat bite fever.
· It is a drug of choice for anthrax actinomycosis.
· Prophylactically it is used for bacterial
endocarditis and surgical infections.
Contraindications: Hypersensitivity,
rash, itching, urticaria, fever, wheezing, angioneuratic
edema, Allergic diathesis, super infections and
Zarrisch Herxheimer reactions.
Dosage: 200 mg- 800 mg thrice
a day.
Presentation: Pen-G 400mg
as 30x6 tablets in a box.
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