 Composion:
Each Tablet contains:
Ibuprofen : 400 mg
Paracetamol : 325 mg
DESCRIPTION:
Laboflam combines the above two ingredients :
Ibuprofen is a non- steroidal anti-inflammatory
agent & possesses analgesic and anti-inflammatory
activities. Controlled studies have demonstrated
that Ibuprofen is a more effective analgesic than
propoxyphene for the relief of episiotomy pain,
pain following dental extraction procedures and
for the relief of the symptoms of primary dysmenorrhoea.
Ibuprofen is rapidly absorbed when administered
orally. Peak serum Ibuprofen levels are generally
attained one or two hours of administration. There
is no evidence of drug accumulation or enzyme
induction. Paracetamol is the main metabolite
of phenacetin, without the side effects of phenacetin.
The efficiency of paracetamol as an analgesic
and antipyretic is equivalent to that of acetylsalicylic
acid, but it has no anti-inflammatory properties.
Paracetamol has no effect on the prothrombine
time and does not appear to produce significant
changes in the gastric mucosa, paracetamol is
rapidly and almost completely absorbed from the
gastrointestinal tract following oral administration.
Peak plasma levels occur in about ½ to
2 hours after administration. Approximately 20%
to 50% is bound to plasma proteins and is metabolised
in the liver largely to glucuronide and sulfate
conjugates and eliminated in the urine.
INDICATIONS:
For the relief of pains of minor and middle intensity
such as headache, neuralgia, myalgia. Arthralgia,
toothache, dysmenorrhoea, less effective in postoperative
and postpartum pain, as antipyretic in the treatment
of fever, relief of signs and symptoms of rheumatoid
arthritis and osteoarthritis.
CONTRAINDICATION:
Laboflam should not be used in patients who
have previously exhibited hypersensitivity to
Ibuprofen & Paracetamol or in individuals
with syndrome of nasal polyps, angiodema and
bronchospastic reactivity to aspirin or other
non-steroidal anti-inflammatory agents.
ADVERSE EFFECTS:
Large doses taken for a long period can cause
gastic distress, hemolytic anaemia, agranulocytosis,
urticaria, rash, fever, hypoglycemia, drowsiness,
severe hepatic damage and may lead to death.
DOSAGE: ADULTS : 3 to 4 Tablets
per day or as prescribed by the physician.
CHILDREN: 5 years and above
1 to 2 Tablets per day.
PRESENTATION: Laboflam is
available as 20x10 Tablets in a Multicarton. |
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