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Composition:-
Each 5 ml contains
Amoxycillin trihydrate
Equivelent to Amoxycillin………..125
mg./ 30 ml
DESCRIPTION:-
It is a semi-synthetic amino penicillin, an analogue
of Ampicillin,with a Good spectrum of bactericidal
activity against many gram-positive and gram-negative
micro-organisms. Amoxycillin is stable in presence
of gastric acid and may be given without regard
to meals. It acts through inhibition of biosynthesis
of cell wall mucopeptide and bacterial cell explodes
due to internal pressure. Its oral absorption
is better and has higher and more sustained blood
levels. It has low incidences of diarrhoea. It
is active against shigella and H.Influenza.It
is also more active against those microbes which
are sensitive to Penicillin G ; in addition many
gram negative bacilli like E.Colli, proteus, Salmonella
are inhibited .
Indications: - § Respiratory Tract infections
including Bronchitis, sinusitis, otitis media.
§ Genito-urinary, skin and soft tissue
infections. § ENT infections due to susceptible
strains of Gram negative organisms like. H.influenzae,
E.coli, P.mirabilis and N.gonorrhoea. Gram positive
organisms like streptococci (including streptococcus
faecalis) D.pneumoniae and non-penicillase producing
staphylococci.
Contra-indications: - Individuals
with a history of an allergic reaction to the
penicillins.
Paediatrics : Safe.
Children : Safe
Side effects: Nausea, vomiting
and diarrhoea. Urticaria, skin rashes
and serum sickness.
Dosage: Children: 20mg/ kg body
wt. in 3 divided doses.
PRESENTATION: - Available as
30 ml, 60 ml, 100 ml bottles. |
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