DESCRIPTION: -
It is semi-synthetic amino penicillin, an analogue of ampicillin, with a Good spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Amoxycillin is stable in presence of gastric acid and may be given without regard to meals. It acts through inhibition of biosynthesis of cell wall mucopeptide and bacterial cell explodes due to internal pressure. Its oral absorption is better and has higher and more sustained blood levels. It has low incidences of diarrhoea. It is active against shigella and H.Influenza.It is also more active against those microbes which are sensitive to Penicillin G; in addition many gram-negative bacilli like E.Colli, proteus, Salmonella are inhibited.
Indications: -
§ Respiratory Tract infections including Bronchitis, sinusitis, otitis media.
§ Genito-urinary, skin and soft tissue infections.
§ ENT infections due to susceptible strains of Gram-negative organisms like. H.influenzae, E.coli, P.mirabilis and N.gonorrhoea.Gram positive organisms like streptococci (including streptococcus faecalis) D.pneumoniae and non-penicillase producing staphylococci.
Contra-indications: - Individuals with a history of an allergic reaction to the penicillins.
Paediatrics: Safe.
Pregnancy: No evidence of risk.
Lactation: safe.
Elderly: No known problem.
Side effects: Nausea, vomiting and diarrhoea. Urticaria, skin rashes
And serum sickness.
Dosage: Adult: 250mg -1 gm thrice daily.
Children: 20mg/ kg body wt. in 3 divided doses.
PRESENTATION: -

§ Labmox 250 mg available as 20 x 10 capsule in one multicarton.
§ Labmox 500 mg available as 10 x 10 capsule in one multicarton.